Author

Chandrakant Tayade

Queen's UniversityORCID 0000-0001-9062-050XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Assay:proteomics· 3 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Danielle J SisnettiD· 4 shared Katherine B ZutautasiD· 4 shared Alison McCallioniD· 2 shared Bruce A. LesseyiD· 2 shared Harshavardhan LingegowdaiD· 2 shared Jaelis P. HolmesiD· 2 shared Olga BougieiD· 2 shared Asha Ravishanker· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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4 shared papersImmunology

Danielle J SisnettORCID

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4 papers

Recent·Most cited

Endometriosis patient-derived small extracellular vesicles carry unique immune, proteomic and lipidomic signatures associated with mild and severe endometriosis

Jaelis P. Holmes, Katherine B Zutautas, Danielle J Sisnett, Donya Hayati, Olga Bougie, Bruce A. Lessey, Chandrakant Tayade

This study identifies unique immune, proteomic, and lipidomic signatures in endometriosis-derived small extracellular vesicles associated with disease severity.

bioRxiv · Aug 18, 2026 · PreprintMolecular Biology

An investigation of the IL-23/Th17 axis and transcriptomic profiles of T helper subsets in endometriosis

Danielle J Sisnett, Katherine B Zutautas, Jaelis P. Holmes, Jessica Pudwell, Kira King, Olga Bougie, Chandrakant Tayade

This study investigates the IL-23/Th17 axis and transcriptomic profiles of T helper subsets in endometriosis, revealing immune remodeling and a distinct Th17 cell phenotype.

bioRxiv · Jun 12, 2026 · PreprintImmunology

Contributions of T helper 9 cells in endometriosis-associated inflammation and lesion growth

Alison McCallion, Danielle J Sisnett, Katherine B Zutautas, Priyanka Yolmo, Harshavardhan Lingegowda, Asha Ravishanker, Dan Vo Hoang, Chandrakant Tayade

This study investigates the role of Th9 cells in endometriosis by analyzing human tissue samples, in vitro experiments, and a mouse model, finding increased IL-9-positive cells and pro-inflammatory mediators in lesions.

The Journal of Immunology · May 1, 2026Peer-reviewedImmunology

Thymic stromal lymphopoietin contributes to endometriotic lesion proliferation and disease-associated inflammation.

Stanimira Aleksieva, Harshavardhan Lingegowda, Danielle J Sisnett, Alison McCallion, Katherine B Zutautas, Dan Hoang Nguyet Vo, Timothy J. Childs, Bruce A. Lessey, Chandrakant Tayade

This study shows TSLP is overexpressed in endometriotic lesions and promotes cell survival and Th2 inflammation, supporting lesion proliferation.

The Journal of Immunology · Feb 24, 2025Peer-reviewedImmunology