Author

Bruce A. Lessey

Atrium Health Wake Forest BaptistORCID 0000-0002-8451-2817Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Assay:metabolomics· 1

Frequent Co-Authors

Chandrakant TayadeiD· 2 shared Danielle J SisnettiD· 2 shared Katherine B ZutautasiD· 2 shared Alison McCallioniD· 1 shared Dan Hoang Nguyet VoiD· 1 shared Donya HayatiiD· 1 shared Harshavardhan LingegowdaiD· 1 shared Jaelis P. HolmesiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMolecular Biology

Chandrakant TayadeORCID

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2 papers

Recent·Most cited

Endometriosis patient-derived small extracellular vesicles carry unique immune, proteomic and lipidomic signatures associated with mild and severe endometriosis

Jaelis P. Holmes, Katherine B Zutautas, Danielle J Sisnett, Donya Hayati, Olga Bougie, Bruce A. Lessey, Chandrakant Tayade

This study identifies unique immune, proteomic, and lipidomic signatures in endometriosis-derived small extracellular vesicles associated with disease severity.

bioRxiv · Aug 18, 2026 · PreprintMolecular Biology

Thymic stromal lymphopoietin contributes to endometriotic lesion proliferation and disease-associated inflammation.

Stanimira Aleksieva, Harshavardhan Lingegowda, Danielle J Sisnett, Alison McCallion, Katherine B Zutautas, Dan Hoang Nguyet Vo, Timothy J. Childs, Bruce A. Lessey, Chandrakant Tayade

This study shows TSLP is overexpressed in endometriotic lesions and promotes cell survival and Th2 inflammation, supporting lesion proliferation.

The Journal of Immunology · Feb 24, 2025Peer-reviewedImmunology