Christopher M. West

Potential for the Terminal SKP1 Glycosyltransferase to Exert Non-Enzymatic Control of SKP1 in Toxoplasma gondii

This study shows GAT1, a glycosyltransferase, specifically binds monomeric SKP1 in Toxoplasma gondii, altering its dimer/monomer balance and affecting FBP interactions.

Global characterization of Dictyostelium discoideum gene expression changes under hypoxic conditions

This study characterizes transcriptomic and proteomic changes in Dictyostelium discoideum under hypoxic conditions, revealing extensive gene and protein expression remodeling.

Novel antibodies detect nucleocytoplasmic O-fucose in protist pathogens, cellular slime molds, and plants

This paper develops specific antibodies to detect O-fucose on nucleocytoplasmic proteins in protists, slime molds, and plants, revealing conservation of the O-fucome across species.

The GPI sidechain of Toxoplasma gondii prevents parasite pathogenesis

This paper identifies and characterizes glycosyltransferases in Toxoplasma gondii that modify GPI sidechains, showing that their absence increases parasite virulence.