VANGL2 shapes the mouse heart tube from adjacent epithelia and without planar polarity
Paul Palmquist‐Gomes, Gaëlle Letort, A. Hegde, José María Pérez-Pomares, Sigolène M. Meilhac
This study identifies novel epithelial roles of VANGL2 in shaping the mouse heart tube through cell rearrangements and midline symmetry control, independent of planar polarity.
bioRxiv · Sep 5, 2025 · PreprintDevelopmental Biology