Author

Dongyan Chen

Chinese Academy of SciencesORCID 0000-0001-9079-6900Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:zebrafish· 2 Assay:scATAC-seq· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Shu Kai LiiD· 2 shared Yubo FaniD· 2 shared Atsuko Shimada· 1 shared Dake ZhangiD· 1 shared Deng Pan· 1 shared Hailang Fan· 1 shared Hiroyuki TakedaiD· 1 shared Jiang-Fan Yin· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersDevelopmental Biology

Shu Kai LiORCID

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2 papers

Recent·Most cited

Chromatin remodeling integrates vertebrate body axis elongation and cell fate determination

Shu Kai Li, Nguyen tien viet, Wanjuan Bu, Hailang Fan, Deng Pan, Zixing Wang, Dongyan Chen, Dake Zhang, Yuliang Jin, Yubo Fan, Jing Du

This study shows that chromatin remodeling coordinates cell fate and movement during zebrafish tailbud elongation by modulating nuclear volume and gene expression.

bioRxiv · Mar 11, 2025 · PreprintDevelopmental Biology

Mechanically Sensitive HSF1 is a Key Regulator of Left-Right Symmetry Breaking in Zebrafish Embryos

Jing Du, Shu-Kai Li, Liu‐Yuan Guan, Zheng Guo, Jiang-Fan Yin, Li Gao, Toru Kawanishi, Atsuko Shimada, Qiuping Zhang, Lisha Zheng, Yiyao Liu, Xi‐Qiao Feng, Lin Zhao, Dongyan Chen, Hiroyuki Takeda, Yubo Fan

This study identifies HSF1 as a mechanically sensitive regulator of left-right symmetry breaking in zebrafish embryos through nodal flow-induced gene expression asymmetry.

iScience · Sep 9, 2023Peer-reviewedDevelopmental Biology