Author

Leland C. Sudlow

Washington University in St. LouisORCID 0000-0001-9096-8450Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Approach:statistical model· 2 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Mikhail Y. BereziniD· 3 shared Junwei DuiD· 2 shared Hridoy Biswas· 1 shared Igor D. LuzhanskyiD· 1 shared Joshua D. MitchelliD· 1 shared Junwei DuiD· 1 shared Shamim Ara MollahiD· 1 shared Zhimu WangiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 15 mutual co-author links

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3 shared papersBioinformatics

Mikhail Y. BerezinORCID

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3 papers

Recent·Most cited

BioinformaticsbioRxivPreprintFeb 10, 2026

thematicGO: A Keyword-Based Framework for Interpreting Gene Ontology Enrichment via Biological Themes

Zhimu Wang, Leland C. Sudlow, Junwei Du, Mikhail Y. Berezin

thematicGO organizes GO enrichment terms into biological themes to reduce redundancy and improve readability in transcriptomic studies.

1 citation

bulk RNA-seqstatistical model

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BioinformaticsbioRxivPreprintFeb 11, 2024

Identification Drug Targets for Oxaliplatin-Induced Cardiotoxicity without affecting cancer treatment through Inter Variability Cross-Correlation Analysis (IVCCA)

Junwei Du, Leland C. Sudlow, Hridoy Biswas…·Mikhail Y. Berezin

The paper introduces IVCCA, a bioinformatics tool to identify drug targets for oxaliplatin-induced cardiotoxicity without affecting cancer treatment, finding new pathways like energy metabolism as potential therapeutic targets.

4 citations

mousebulk RNA-seq

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NeurosciencebioRxivPreprintOct 5, 2023

DRG Explant Model: Elucidating Mechanisms of Oxaliplatin-Induced Peripheral Neuropathy and Identifying Potential Therapeutic Targets

Junwei Du, Leland C. Sudlow, Igor D. Luzhansky, Mikhail Y. Berezin

3 citations

mouseexperimental assay

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