Author

Anthony Spinella

Boston UniversityORCID 0000-0001-9135-7643Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:machine learning (classical)· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1

Frequent Co-Authors

Lina KroehlingiD· 2 shared Stefano MontiiD· 2 shared Xaralabos VarelasiD· 2 shared Andrew CheniD· 1 shared Eric R. ReediD· 1 shared Maria A. KukuruzinskaiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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2 shared papersCancer Biology

Lina KroehlingORCID

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2 papers

Recent·Most cited

Age-based shifts in multicellular community organization and abundance in HPV-Negative Head and Neck Cancer

Lina Kroehling, Anthony Spinella, Xaralabos Varelas, Stefano Monti

This study identifies age-related changes in cellular composition and organization in HPV-negative head and neck cancer using single-cell data, highlighting MDK as a key factor in stromal remodeling and immunosuppression.

bioRxiv · Nov 2, 2026 · PreprintCancer Biology

A highly resolved integrated single-cell atlas of HPV-negative head and neck cancer

Lina Kroehling, Andrew Chen, Anthony Spinella, Eric R. Reed, Maria A. Kukuruzinska, Xaralabos Varelas, Stefano Monti

The paper integrates six single-cell datasets to create a high-resolution atlas of HPV-negative HNSCC, revealing new cell populations and associations between transcriptional signatures and clinical outcomes.

Communications Medicine · Mar 11, 2026Peer-reviewedCancer Biology