Lina Kroehling

This study identifies age-related changes in cellular composition and organization in HPV-negative head and neck cancer using single-cell data, highlighting MDK as a key factor in stromal remodeling and immunosuppression.

The paper integrates six single-cell datasets to create a high-resolution atlas of HPV-negative HNSCC, revealing new cell populations and associations between transcriptional signatures and clinical outcomes.

This study creates a large integrated single-cell RNA-seq atlas of human breast cancers, revealing tumor microenvironment heterogeneity and survival-associated cell states across multiple datasets.

This study shows that dietary serine restriction alters H3K27me3 and H3K4me3 histone modifications, reducing tumor growth and plasticity in head and neck cancer.

This study shows LSD1 inhibition enhances antitumor immunity in HNSCC by upregulating MHC-I and activating the IFNγ-CXCL9-CXCR3 axis through dendritic cells and CD8+ T cells.