Seppo Meri

The paper investigates the impact of CFHR gene deletions on kidney transplant rejection risk and identifies associated SNPs and protein expression changes.

The paper identifies CFHR5 variants that reduce AMD risk by lowering FHR-5 levels and altering complement pathway activity.

The paper analyzes complement molecule expression and deposition in human pre-implantation embryos, showing complement activation and defense mechanisms at early stages of development.

The paper demonstrates asymmetry in the catalytic cycle of membrane-bound pyrophosphatases using a non-phosphorous allosteric inhibitor bound to Thermotoga maritima enzyme.