Adrian Goldman

This study identifies three novel VTC binding partners in Leishmania tarentolae acidocalcisomes using BioID and confirms their interactions through microscopy and structural predictions.

This study investigates the inhibitory effects of bisphosphonates on Thermotoga maritima mPPase, revealing conformational asymmetry and symmetry-breaking during catalysis.

This study expresses, purifies, and characterizes the Plasmodium falciparum mPPase, identifying three compounds with micromolar IC50 activity against it.

The paper determines the crystal structures of unloaded and cargo-loaded VSR1-Nt, revealing two cargo binding sites and a calcium-dependent mechanism for cargo binding and release.

The paper demonstrates asymmetry in the catalytic cycle of membrane-bound pyrophosphatases using a non-phosphorous allosteric inhibitor bound to Thermotoga maritima enzyme.