Timo Tuuri

This study finds no significant transcriptomic differences between PMOS and control iPSC lines, highlighting donor variation as the main source of expression differences.

The paper uses multimodal single-cell profiling to show how puberty and chemotherapy affect pediatric ovarian tissue, identifying vulnerabilities and a potential biomarker.

The paper identifies hsa-miR-92a-3p as a regulator of cell-cycle and signaling programs during human extra-embryonic lineage commitment using single-cell and bulk RNA-seq data.

This study shows that hypoxia (6% O2) improves blastocyst formation in bovine embryos compared to normoxia (20% O2) and ultrahypoxia (2% O2), with normoxia altering energy metabolism and reducing blastocyst rates.

This study examines DNA methylation, imprinting, and gene expression in placentas from ART and control groups, identifying molecular changes linked to ART and subfertility.

This study shows that DUX4 regulates the oocyte-to-embryo transition in humans by activating enhancers and promoting genome reprogramming.

The paper analyzes complement molecule expression and deposition in human pre-implantation embryos, showing complement activation and defense mechanisms at early stages of development.