Author

Sivakumar Vadivel Gnanasundram

Indian Institute of Technology PalakkadORCID 0000-0001-9153-0784Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

Bořivoj VojtěšekiD· 1 shared Isabelle C. Kos‐BrauniD· 1 shared Lixiao Wang· 1 shared Martin KošiD· 1 shared Ondřej BonczekiD· 1 shared Robin FåhræusiD· 1 shared Sa CheniD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 11 mutual co-author links

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1 shared paperMolecular Biology

Bořivoj VojtěšekORCID

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2 papers

Recent·Most cited

Molecular BiologyRNAPeer-reviewedApr 17, 2026

Cancer-associated synonymous mutations reveal stress signal-dependent mRNA folding that selectively modulates protein function.

Sivakumar Vadivel Gnanasundram, Lixiao Wang, Sa Chen…·Robin Fåhræus

The paper shows that cancer-associated synonymous mutations affect mRNA folding during DNA damage, altering p53 function and downstream gene expression.

1 citation

humanbulk RNA-seq

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Molecular BiologybioRxivPreprintMar 31, 2019

Two molecules of Has1 RNA helicase function simultaneously in the biogenesis of small and large ribosomal subunits

Sivakumar Vadivel Gnanasundram, Isabelle C. Kos‐Braun, Martin Koš

The paper shows Has1 RNA helicase functions in both small and large ribosomal subunit biogenesis by binding to multiple rRNA regions, with distinct requirements for its catalytic activity.

DOI 10.1101/594762

experimental assay

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