Author

Sa Chen

Umeå UniversityORCID 0000-0002-4834-1221Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Bořivoj VojtěšekiD· 1 shared Lixiao Wang· 1 shared Ondřej BonczekiD· 1 shared Robin FåhræusiD· 1 shared Sivakumar Vadivel GnanasundramiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperMolecular Biology

Bořivoj VojtěšekORCID

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1 paper

Recent·Most cited

Molecular BiologyRNAPeer-reviewedApr 17, 2026

Cancer-associated synonymous mutations reveal stress signal-dependent mRNA folding that selectively modulates protein function.

Sivakumar Vadivel Gnanasundram, Lixiao Wang, Sa Chen…·Robin Fåhræus

The paper shows that cancer-associated synonymous mutations affect mRNA folding during DNA damage, altering p53 function and downstream gene expression.

1 citation

humanbulk RNA-seq

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