NeuroscienceBrain CommunicationsPeer-reviewed
Metabolic alterations in the absence of a detectable neuromuscular phenotype in novel genomically humanised SOD1A4V mice.
David Thompson, Chloe Williams, Georgia Price…·Thomas J. Cunningham
This study generates and analyzes a novel genomically humanised SOD1A4V mouse model, revealing metabolic dysfunction through multi-omic analyses and identifying it as a potential pre-symptomatic ALS model.
DOI 10.1093/braincomms/fcag302