Author

Katerina D Melnyk

National Institutes of HealthORCID 0000-0001-9167-5801Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Organism:mouse· 1

Frequent Co-Authors

Alana L. GibsoniD· 1 shared Arturo A. IncaoiD· 1 shared Avani V. MylvaraiD· 1 shared Burha RasooliD· 1 shared Charles P. VendittiiD· 1 shared Cristin D. DavidsoniD· 1 shared Devin M FulleriD· 1 shared Dominick Pierre-JacquesiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperNeuroscience

Alana L. GibsonORCID

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2 papers

Recent·Most cited

NeuroscienceLife Science AlliancePeer-reviewedMar 18, 2026

Optimization of systemic AAV9 gene therapy in Niemann-Pick disease type C1 mice

Avani V. Mylvara, Alana L. Gibson, Tansy Gu…·William J. Pavan

This study evaluates the efficacy of systemic AAV9-hNPC1 gene therapy in NPC1 mouse models, finding that higher doses and earlier treatment improve survival and slow disease progression.

2 citationstop 3%

mouseexperimental assay

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Cell BiologybioRxivPreprintMar 24, 2025

ATG2A interacts with RAB1A and ARFGAP1 positive membranes during autophagosome biogenesis

Devin M Fuller, Yumei Wu, Florian Schueder…·Thomas James Melia

This paper identifies RAB1A and ARFGAP1-positive membranes as essential for autophagosome biogenesis, interacting with ATG2A to support lipid transport during autophagosome formation.

DOI 10.1101/2025.03.24.645038

experimental assaycell signaling & trafficking

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