Thomas James Melia

This paper identifies RAB1A and ARFGAP1-positive membranes as essential for autophagosome biogenesis, interacting with ATG2A to support lipid transport during autophagosome formation.

This study quantifies the timeline of nuclear autophagy in yeast, revealing a role for Dnm1 in nuclear envelope remodeling during cargo removal.

The paper introduces a DNA-origami NanoTrap to study diffusion barriers formed by FG-nups and finds that motif type, density, and arrangement are critical for barrier effectiveness.

This paper observes GABARAPL1-mediated membrane tethering and curvature-dependent partitioning using GUVs and micromanipulation.