Author

Aaron J. Ciechanover

Technion – Israel Institute of TechnologyORCID 0000-0001-9184-8944Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:protein structure· 1

Frequent Co-Authors

Asuka Alvarado· 1 shared Donald P. PizzoiD· 1 shared Evan Y. Snyder· 1 shared Fang Xiong· 1 shared Haizhan JiaoiD· 1 shared Hongli HuiD· 1 shared Iris S. Huang· 1 shared Jiao ZhouiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Asuka Alvarado

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Author profile →

1 paper

Recent·Most cited

The cryo-EM-delineated mechanism underlying mimicry of CXCR4 agonism enables widespread stem cell neuroprotection in a mouse model of ALS

Xiaohong Sang, Haizhan Jiao, Qian Meng, Fang Xiong, Kartik S. Sundaram, Jiao Zhou, Yan Xu, Asuka Alvarado, Ruslan L. Nuryyev, Jitka Ourenik, Václav Ourednik, Iris S. Huang, Xiang Liu, Yuheng Mei, Tingli Qian, , Ziwei Huang

The paper demonstrates a synthetic dual-moiety strategy to design CXCR4 agonist peptides that mimic SDF-1, showing therapeutic benefit in a mouse model of ALS through neuroprotection.

bioRxiv · Jul 8, 2025 · PreprintNeuroscience