Author

Qian Yi Lee

Institute for Stem Cell Biology and Regenerative MedicineORCID 0000-0001-9200-0910Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Marius WernigiD· 3 shared Cheen Euong AngiD· 2 shared Howard Y. ChangiD· 2 shared Moritz MalliD· 2 shared Orly L. Wapinski· 2 shared Victor Hipolito OlmosiD· 2 shared Aadit NarayanaswamyiD· 1 shared Anand Srivastava· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersNeuroscience

Marius WernigORCID

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3 papers

Recent·Most cited

GenomicsbioRxivPreprintDec 2, 2020

THE DYNAMIC INTERPLAY BETWEEN HOMEODOMAIN TRANSCRIPTION FACTORS AND CHROMATIN ENVIRONMENT REGULATES PRONEURAL FACTOR OUTCOMES

Cheen Euong Ang, Victor Hipolito Olmos, Bo Zhou…·Marius Wernig

The paper shows that co-expressing NGN2 with EMX1 generates homogeneous glutamatergic neurons from human pluripotent stem cells, with altered transcriptional output and chromatin binding compared to NGN2 alone.

3 citations

humanbulk RNA-seq

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NeuroscienceeLifePeer-reviewedJan 14, 2019

Global DNA methylation remodeling during direct reprogramming of fibroblasts to neurons

Chongyuan Luo, Qian Yi Lee, Orly L. Wapinski…·Joseph R. Ecker

This study examines DNA methylation changes during fibroblast-to-neuron reprogramming, identifying key factors and mechanisms involved in epigenomic remodeling.

76 citationstop 4%

mouseDNA methylation

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NeuroscienceeLifePeer-reviewedJan 10, 2019

The novel lncRNA lnc-NR2F1 is pro-neurogenic and mutated in human neurodevelopmental disorders

Cheen Euong Ang, Qing Ma, Orly L. Wapinski…·Howard Y. Chang

The paper identifies lnc-NR2F1 as a pro-neurogenic lncRNA mutated in neurodevelopmental disorders through genetic and functional studies.

75 citationstop 5%

humanstatistical model

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