Author

Orly L. Wapinski

Harvard University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Approach:Bayesian inference· 1

Frequent Co-Authors

Howard Y. ChangiD· 2 shared Marius WernigiD· 2 shared Qian Yi LeeiD· 2 shared Anand Srivastava· 1 shared Anders W. RasmusseniD· 1 shared Bradley P. CoeiD· 1 shared Brian T. DoiD· 1 shared Cheen Euong AngiD· 1 shared

Activity by Year

2019-2019 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersNeuroscience

Howard Y. ChangORCID

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Author profile →

3 papers

Recent·Most cited

Characterizing the epigenetic landscape of cellular populations from bulk and single-cell ATAC-seq information.

Mariano I. Gabitto, Anders W. Rasmussen, Orly L. Wapinski, Kathryn C. Allaway, Nicholas John Carriero, Gord Fishell, Richard Bonneau

The paper introduces ChromA, a Bayesian method for analyzing ATAC-seq data to annotate chromatin accessibility, improving cell type identification and correcting biases in single-cell data.

bioRxiv · Mar 4, 2019 · PreprintBioinformatics

Global DNA methylation remodeling during direct reprogramming of fibroblasts to neurons

Chongyuan Luo, Qian Yi Lee, Orly L. Wapinski, Rosa Castanon, Joseph R. Nery, Moritz Mall, Michael S. Kareta, Sean M. Cullen, Margaret A. Goodell, Howard Y. Chang, Marius Wernig, Joseph R. Ecker

This study examines DNA methylation changes during fibroblast-to-neuron reprogramming, identifying key factors and mechanisms involved in epigenomic remodeling.

eLife · Jan 14, 2019Peer-reviewedNeuroscience

The novel lncRNA lnc-NR2F1 is pro-neurogenic and mutated in human neurodevelopmental disorders

Cheen Euong Ang, Qing Ma, Orly L. Wapinski, Shenghua Fan, Ryan A. Flynn, Qian Yi Lee, Bradley P. Coe, Masahiro Onoguchi, Victor Hipolito Olmos, Brian T. Do, Lynn Dukes‐Rimsky, Jin Xu, Koji Tanabe, Liangjiang Wang, Ulrich Elling, , Howard Y. Chang

The paper identifies lnc-NR2F1 as a pro-neurogenic lncRNA mutated in neurodevelopmental disorders through genetic and functional studies.

eLife · Jan 10, 2019Peer-reviewedNeuroscience