Author

Edmund J. Carvalho

University of PennsylvaniaORCID 0000-0001-9218-4318Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1

Frequent Co-Authors

David Padron NardoiD· 1 shared James L. RileyiD· 1 shared Kaitlin A. ReadiD· 1 shared Meidi GuiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperImmunology

David Padron NardoORCID

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1 paper

Recent·Most cited

ImmunologybioRxivPreprintJul 26, 2024

Rab5 Overcomes CAR T Cell Dysfunction Induced by Tumor-Mediated CAR Capture

Meidi Gu, Edmund J. Carvalho, Kaitlin A. Read…·James L. Riley

This study shows that overexpressing Rab5 prevents CAR internalization by tumors, maintains CAR surface expression, and improves CART efficacy against solid tumors.

3 citations

mouseflow cytometry

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