Author

Hélène Doerflinger

University of CambridgeORCID 0000-0001-9237-5210Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Daniel St JohnstoniD· 2 shared Amandine PalandriiD· 1 shared Noah Jackaman· 1 shared Vitaly L. ZimyaniniD· 1 shared Xixi Zhu· 1 shared Y T CheniD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 11 mutual co-author links

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2 shared papersCell Biology

Daniel St JohnstonORCID

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2 papers

Recent·Most cited

An aPKC rheostat induces apical contraction in response to epithelial stretching

Hélène Doerflinger, Amandine Palandri, Noah Jackaman, Y T Chen, Xixi Zhu, Daniel St Johnston

The paper shows that aPKC inhibition in Drosophila follicle cells triggers apical contraction in response to stretching by activating Yurt through a conserved pathway.

bioRxiv · May 12, 2026 · PreprintCell Biology

The Drosophila anterior-posterior axis is polarized by asymmetric myosin activation

Hélène Doerflinger, Vitaly L. Zimyanin, Daniel St Johnston

This paper shows that asymmetric myosin activation polarizes the Drosophila anterior-posterior axis by recruiting and maintaining Par-1 at the posterior cortex.

Current Biology · Dec 1, 2021Peer-reviewedDevelopmental Biology