Author

James W. Frederiksen

Duke UniversityORCID 0000-0001-9246-0108Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Bruce A. SullengeriD· 1 shared Charlene Vongai ChabataiD· 1 shared Haixiang YuiD· 1 shared Lei KeiD· 1 shared Nabil K. ThaljiiD· 1 shared Prakash A. PateliD· 1 shared

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2024-2024 · peak 1/yr

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1 shared paperBiochemistry

Bruce A. SullengerORCID

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1 paper

Recent·Most cited

BiochemistryArteriosclerosis Thrombosis and Vascular BiologyPeer-reviewedNov 21, 2024

Andexanet alfa-associated heparin resistance in cardiac surgery: mechanism and in vitro perspectives

Charlene Vongai Chabata, Haixiang Yu, Lei Ke…·Nabil K. Thalji

This study investigates how andexanet alfa causes heparin resistance in cardiac surgery, showing it sequesters heparin-bound antithrombin and creates a triphasic response to heparin.

12 citations

humanexperimental assay