Sreelekshmy Mohandas

Construction of an Immunoinformatics-Based Multi-Epitope Vaccine Candidate targeting Kyasanur Forest Disease Virus

This study develops a multi-epitope vaccine candidate against KFDV using immunoinformatic tools, showing stable interaction with TLR2-TLR6 and codon optimization for prokaryotic expression.

Protective immunity of the primary SARS-CoV-2 infection reduces disease severity post re-infection with Delta variants in Syrian hamsters

This study shows that re-infection with Delta and B.1 variants in recovered Syrian hamsters results in reduced disease severity compared to primary infection, while Delta AY.1 causes milder disease and maintains neutralizing antibody responses.

SARS-CoV-2 Delta variant pathogenesis and host response in Syrian hamsters

This study compares the pathogenicity and host response of SARS-CoV-2 Delta and B.1.617.3 variants with B.1 in Syrian hamsters, finding increased disease severity and transmission potential for Delta.