Pragya Dhruv Yadav

Complete Genome Sequencing and Molecular Characterization of Indigenous Enterovirus A71 Genogroups D and G of India

The paper characterizes two indigenous EV-A71 genogroups (D and G) from India through genome sequencing and phylogenetic analysis, revealing their distinct evolutionary paths and geographic restriction.

Construction of an Immunoinformatics-Based Multi-Epitope Vaccine Candidate targeting Kyasanur Forest Disease Virus

This study develops a multi-epitope vaccine candidate against KFDV using immunoinformatic tools, showing stable interaction with TLR2-TLR6 and codon optimization for prokaryotic expression.

Protective immunity of the primary SARS-CoV-2 infection reduces disease severity post re-infection with Delta variants in Syrian hamsters

This study shows that re-infection with Delta and B.1 variants in recovered Syrian hamsters results in reduced disease severity compared to primary infection, while Delta AY.1 causes milder disease and maintains neutralizing antibody responses.

SARS-CoV-2 Delta derivatives impact on neutralization of Covishield recipient sera

This study evaluates the neutralizing antibody response of different groups against SARS-CoV-2 Delta and its derivatives using PRNT50.

Comparable neutralization of SARS-CoV-2 Delta AY.1 and Delta in individuals sera vaccinated with BBV152

The paper evaluates the neutralizing activity of sera from vaccinated and recovered individuals against SARS-CoV-2 Delta, Delta AY.1, and B.1.617.3 variants, finding reduced but still effective neutralization.

SARS-CoV-2 Delta variant pathogenesis and host response in Syrian hamsters

This study compares the pathogenicity and host response of SARS-CoV-2 Delta and B.1.617.3 variants with B.1 in Syrian hamsters, finding increased disease severity and transmission potential for Delta.

Convergent evolution of SARS-CoV-2 spike mutations, L452R, E484Q and P681R, in the second wave of COVID-19 in Maharashtra, India

The paper analyzes spike protein mutations in SARS-CoV-2 variants from Maharashtra, India, identifying lineage B.1.617 with mutations linked to increased transmissibility and reduced antibody neutralization.

Neutralization of UK-variant VUI-202012/01 with COVAXIN vaccinated human serum

Sera from 26 BBV152/COVAXIN recipients neutralised the UK variant about as well as a heterologous strain in plaque reduction tests, arguing against escape from vaccine-induced antibodies.