John W. Cole

Exome Array Analysis of 9,721 ischemic stroke cases from the SiGN Consortium

The paper analyzes exome array data from 9,721 ischemic stroke cases to identify coding variants associated with stroke, finding 15 significant variants, including 13 novel associations.

Genomic Risk Scores and Oral Contraceptive-Associated Ischemic Stroke Risk

The paper evaluates whether a genomic risk score modifies the risk of ischemic stroke associated with oral contraceptive use in premenopausal women.

MRI Radiomic Signature of White Matter Hyperintensities Is Associated with Clinical Phenotypes

This paper develops a radiomic signature from T2-FLAIR MRI images to predict white matter hyperintensities burden and links it to clinical phenotypes.

Sex-specific lesion topographies explain outcomesafter acute ischemic stroke

This study identifies sex-specific lesion patterns in acute ischemic stroke that correlate with stroke severity, highlighting differences in lesion distribution between men and women.

White Matter Hyperintensity Quantification in Large-Scale Clinical Acute Ischemic Stroke Cohorts - The MRI-GENIE Study

The paper presents an automated pipeline for quantifying white matter hyperintensity in acute ischemic stroke cohorts, showing improved accuracy and enabling large-scale analysis.