Author

Kevin Nguyen

Fred Hutch Cancer Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Neuroscience· 2 Genetic & Genomic Medicine· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Organism:Drosophila· 1 Organism:human· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Brady J. GaynoriD· 1 shared Braxton D. MitchelliD· 1 shared Brittany N. TakushiiD· 1 shared Charles C. HongiD· 1 shared Charles L KooperbergiD· 1 shared Courtney Barkley· 1 shared David R. WeiriD· 1 shared Dominik HaddadiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Brady J. GaynorORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Nascent CUT&Tag captures transcription factor binding after chromatin duplication

Matthew Wooten, Kevin Nguyen, Brittany N. Takushi, Kami Ahmad, Steven Henikoff

This study develops Nascent CUT&Tag to measure transcription factor binding on nascent chromatin and finds that GAF recovers faster than PHO in Drosophila cells, with differences in motif length and functional associations.

bioRxiv · Oct 13, 2025 · PreprintGenomics

Exome Array Analysis of 9,721 ischemic stroke cases from the SiGN Consortium

Huichun Xu, Kevin Nguyen, Brady J. Gaynor, Hua Ling, Wei Zhao, Patrick F. McArdle, Timothy D. O’Connor, Oscar Colin Stine, Kathleen A. Ryan, Megan T. Lynch, Jennifer A. Smith, Jessica D. Faul, Yao Hu, Jeffrey Haessler, Myriam Fornage, , Braxton D. Mitchell

The paper analyzes exome array data from 9,721 ischemic stroke cases to identify coding variants associated with stroke, finding 15 significant variants, including 13 novel associations.

Genes · Dec 24, 2022Peer-reviewedGenetic & Genomic Medicine

Mitochondrial fission is a critical modulator of mutant APP-induced neural toxicity

Lauren Y. Shields, Huihui Li, Kevin Nguyen, Hwajin Kim, Zak Doric, Joseph H. Garcia, T. Michael Gill, Dominik Haddad, Keith A. Vossel, Meredith Calvert, Ken Nakamura

This study shows that loss of Drp1 in neurons worsens memory deficits in mice with mutant hAPP, revealing a protective role of mitochondrial fission against hAPP-induced pathology.

Journal of Biological Chemistry · Jan 1, 2021Peer-reviewedNeuroscience

Tgfbr2 in dental pulp cells guides sensory innervation in developing teeth

Courtney Barkley, Rosa A. Serra, Kevin Nguyen, Sarah B. Peters

This study shows that Tgfbr2 in dental pulp mesenchyme regulates paracrine signals that guide sensory innervation of developing teeth.

bioRxiv · Apr 21, 2020 · PreprintNeuroscience