GenomicsCancer CellPeer-reviewed
The Tandem Duplicator Phenotype is a prevalent genome-wide cancer configuration driven by distinct gene mutations
Francesca Menghi, Floris P Barthel, Vinod Kumar Yadav…·Edison T. Liu
The paper identifies three span intervals of tandem duplications in TDP tumors and links them to specific gene mutations and pathways, showing TP53 and BRCA1 loss drives short-span TDPs.
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