Author

Brooke E. Chambers

University of Notre DameORCID 0000-0001-9309-0022Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:zebrafish· 3 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Rebecca A. WingertiD· 3 shared Eleanor G. ClarkiD· 2 shared Gary F. GerlachiD· 2 shared Ignaty LeshchineriD· 2 shared Wolfram GoesslingiD· 2 shared Allison E. GatziD· 1 shared Anna E. Levesque· 1 shared Bridgette E. Drummond· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersDevelopmental Biology

Rebecca A. WingertORCID

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3 papers

Recent·Most cited

Developmental BiologybioRxivPreprintDec 21, 2020

osr1 maintains renal progenitors and regulates podocyte development by promoting wnt2ba through antagonism of hand2

Bridgette E. Drummond, Brooke E. Chambers, Hannah M. Wesselman…·Rebecca A. Wingert

This study identifies Osr1's role in maintaining renal progenitors and regulating podocyte development through Wnt2ba expression, revealing its antagonistic relationship with Hand2.

2 citations

zebrafishexperimental assay

𝕏 PostBluesky

Developmental BiologyDevelopmentPeer-reviewedOct 7, 2020

Kctd15 regulates nephron segment development by repressing Tfap2a activity

Brooke E. Chambers, Eleanor G. Clark, Allison E. Gatz, Rebecca A. Wingert

This study shows that Kctd15 paralogs restrict distal nephron segment development by repressing Tfap2a activity in zebrafish.

22 citations

zebrafishbulk RNA-seq

𝕏 PostBluesky

Developmental BiologyDevelopmentPeer-reviewedJan 1, 2019

Tfap2a is a novel gatekeeper of differentiation in renal progenitors during kidney development

Brooke E. Chambers, Gary F. Gerlach, Eleanor G. Clark…·Rebecca A. Wingert

This study identifies tfap2a as a key regulator of distal nephron segment differentiation in zebrafish, revealing its role in controlling gene regulatory networks and specialized metabolic functions.

42 citations

zebrafishstatistical model

𝕏 PostBluesky