Author

Bo Hua

Harvard UniversityORCID 0000-0001-9313-4670Unclaimed ORCID profile · follow to get notified of new preprints

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Bo Hua3 papers · Harvard University

Biology Disciplines

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Systems Biology· 2

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Organism:yeast· 2 Research Focus:benchmarking· 1

Frequent Co-Authors

Jiayin HongiD· 2 shared Michael SpringeriD· 2 shared Chao TangiD· 1 shared Julius PalmeiD· 1 shared

Activity by Year

2020-2021 · peak 1/yr

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4 top collaborators · 5 mutual co-author links

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2 shared papersSystems Biology

Jiayin HongORCID

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2 papers

Recent·Most cited

Systems BiologyPLoS Computational BiologyPeer-reviewedSep 27, 2021

Computational analysis of GAL pathway pinpoints mechanisms underlying natural variation

Jiayin Hong, Julius Palme, Bo Hua, Michael Springer

The paper identifies key parameters in the GAL pathway that explain natural variation in yeast's response to galactose, using computational modeling and in silico perturbation.

1 citation

yeaststatistical model

𝕏 PostBluesky

Systems BiologyPLoS Computational BiologyPeer-reviewedDec 4, 2020

Computational study on ratio-sensing in yeast galactose utilization pathway

Jiayin Hong, Bo Hua, Michael Springer, Chao Tang

This study uses computational models to show that ratio-sensing in yeast galactose utilization arises from competition between carbon sources for transporters and transcription factors, and reveals design principles for synthetic biology applications.

3 citations

yeaststatistical model

𝕏 PostBluesky