Author

Motonao Osaki

Kyoto UniversityORCID 0000-0001-9315-7805Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Shimon SakaguchiiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

1 paper

Recent·Most cited

ImmunologyImmunityPeer-reviewedApr 1, 2025

Soluble CTLA-4 mainly produced by Treg cells inhibits type 1 inflammation without hindering type 2 immunity to allow for inflammation resolution

Motonao Osaki, Shimon Sakaguchi

This study shows that soluble CTLA-4 from Treg cells inhibits type 1 inflammation while preserving type 2 immunity, aiding inflammation resolution.

51 citationstop 1%

mouseexperimental assay

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