Author

Josef M. Pfeilschifter

Goethe University FrankfurtORCID 0000-0001-9315-9122Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Adam StrzelczykiD· 1 shared Alexandra LucaciuiD· 1 shared Alexia A. ZagourasiD· 1 shared Christian GrefkesiD· 1 shared Christoph WelschiD· 1 shared David J. LeferiD· 1 shared Deepthi Bevara· 1 shared Eva Lueckhoff· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

Adam StrzelczykORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintOct 5, 2026

✦ In-depth digest

Lipocalin-2-expressing red pulp macrophages link ischemic stroke to systemic immune reprogramming in mice and humans

Alexandra Lucaciu, Patrick Wurzel, Stine Rytz Rasmussen…·Rajkumar Vutukuri

Splenic Lcn2 is induced biphasically after mouse stroke and localizes to red pulp macrophages; recombinant LCN2 induces T cell and monocyte hyporesponsiveness and monocyte phagocytosis-ROS uncoupling, with human spleen support.

DOI 10.64898/2026.06.23.733904

mousehuman

𝕏 PostBluesky

Pharmacology & ToxicologyJACC Basic to Translational SciencePeer-reviewedAug 6, 2025

Hydrogen Sulfide Deficiency and Therapeutic Targeting in Cardiometabolic HFpEF: Evidence for Synergistic Benefit with GLP-1/Glucagon Agonism

Jake E. Doiron, Mahmoud H. Elbatreek, Huijing Xia…·David J. Lefer

This study shows H2S deficiency in HFpEF patients and models, and that H2S supplementation or combination with GLP-1/glucagon agonists improves HFpEF outcomes.

9 citations

humanmouse

𝕏 PostBluesky