Author

Shane McDevitt

Temple UniversityORCID 0000-0001-9360-2841Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Agnel J. SfeiriD· 1 shared Ekaterina Kashkina· 1 shared Pedro A. Mateos‐GómeziD· 1 shared Richard T. PomerantziD· 1 shared Sarah Deng· 1 shared Tatiana KentiD· 1 shared Trung HoàngiD· 1 shared

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2017-2017 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperGenetics

Agnel J. SfeirORCID

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1 paper

Recent·Most cited

GeneticsNature Structural & Molecular BiologyPeer-reviewedOct 19, 2017

The helicase domain of Polθ counteracts RPA to promote alt-NHEJ

Pedro A. Mateos‐Gómez, Tatiana Kent, Sarah Deng…·Agnel J. Sfeir

This study shows that the helicase domain of Polθ promotes alt-NHEJ by displacing RPA, leading to increased chromosomal translocations and reduced HR-mediated gene targeting.

189 citationstop 3%

mouseexperimental assay

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