Author

Pedro A. Mateos‐Gómez

New York UniversityORCID 0000-0002-5539-2289Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Agnel J. SfeiriD· 1 shared Ekaterina Kashkina· 1 shared Richard T. PomerantziD· 1 shared Sarah Deng· 1 shared Shane McDevittiD· 1 shared Tatiana KentiD· 1 shared Trung HoàngiD· 1 shared

Activity by Year

2017-2017 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperGenetics

Agnel J. SfeirORCID

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1 paper

Recent·Most cited

The helicase domain of Polθ counteracts RPA to promote alt-NHEJ

Pedro A. Mateos‐Gómez, Tatiana Kent, Sarah Deng, Shane McDevitt, Ekaterina Kashkina, Trung Hoàng, Richard T. Pomerantz, Agnel J. Sfeir

This study shows that the helicase domain of Polθ promotes alt-NHEJ by displacing RPA, leading to increased chromosomal translocations and reduced HR-mediated gene targeting.

Nature Structural & Molecular Biology · Oct 19, 2017Peer-reviewedGenetics