Stage-dependent tau post-translational modifications map the spatiotemporal progression of Alzheimer's disease
Axelle Vanparys, Clémence Balty, Manuel Johanns, Nathalie Kyalu Ngoie Zola, Gaëtan Herinckx, Marine Van Calsteren, Núria Suelves, John L. Woodard, Didier Vertommen, Pascal Kienlen‐Campard, Bernard Jimmy Hanseeuw
This study maps stage-dependent tau post-translational modifications across Alzheimer's disease progression, revealing early phosphorylation and later ubiquitination events associated with tau aggregation.
bioRxiv · Apr 10, 2026 · PreprintNeuroscience