BioinformaticsCell ResearchPeer-reviewed
GeneCompass: Deciphering Universal Gene Regulatory Mechanisms with Knowledge-Informed Cross-Species Foundation Model
Xiaodong Yang, Guole Liu, Guihai Feng…·Zeyuan Zhang
GeneCompass is a cross-species foundation model pre-trained on single-cell transcriptomes from human and mouse, integrating biological knowledge to improve gene regulatory mechanism understanding and downstream tasks.