Pharmacology & ToxicologybioRxivPreprint
On-cell Saturation Transfer Difference (STD) NMR on ion channels: characterizing negative allosteric modulator binding interactions of P2X7.
Serena Monaco, Jacob Browne, Matthew Wallace…·Leanne Stokes
This paper demonstrates on-cell STD NMR for studying P2X7 receptor-ligand interactions, providing binding epitope maps and 3D models for two antagonists.
DOI 10.1101/2025.04.22.649959