Pharmacology & ToxicologyJournal of Medicinal ChemistryPeer-reviewed
Development of a chemical probe to enable characterization of the casein kinase 1γ subfamily
Jacob L. Capener, Thomas Krämer, Frances M. Bashore…·Alison Donnelly Axtman
The paper develops a chemical probe, SGC-CK1γ-1, for the CK1γ subfamily, showing potent and selective inhibition of CK1γ kinases, WNT signaling, and HCMV replication.
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