José Antonio Avilés-Izquierdo

G-CSF associates with poor survival in cutaneous melanoma and promotes metastasis through coordinated effects on macrophages and tumor cells

This study identifies G-CSF as a prognostic biomarker in melanoma and shows it promotes metastasis by enhancing tumor cell invasion and macrophage pro-tumoral activity.

Adverse prognosis of GM-CSF expression in human cutaneous melanoma

This study shows that GM-CSF expression in melanoma and tumor-associated macrophages correlates with poor prognosis and promotes metastasis through pro-inflammatory signaling.

Translating Genetics into Tissue: Inflammatory Cytokine-Producing TAMs and PD-L1 Tumor Expression as Poor Prognosis Factors in Cutaneous Melanoma

The paper identifies inflammatory cytokine-producing TAMs and PD-L1 tumor expression as poor prognosis factors in cutaneous melanoma using single-cell RNA sequencing and microscopy.