Majed Mohamed Magzoub

This paper introduces Shorkie, a DNA language model pretrained on fungal genomes that improves gene expression prediction in budding yeast by capturing regulatory motif dynamics and variant effects.

The paper analyzes the multiome of Diversity Outbred mice to explore how aging and lifespan are related, finding that proteomic changes correlate with biological age rather than chronological age.

The paper introduces ProteoMix, a method using proteomic data to identify epigenetic driver genes, finding that DNA methylation effects are often buffered at the protein level and enriched for cancer-related processes and markers.