Author

Jacob Carey

Johns Hopkins UniversityORCID 0000-0001-9462-206XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:whole-genome sequencing· 2 Approach:Bayesian inference· 1 Research Focus:differential expression· 1 Research Focus:GWAS / association mapping· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Alexander V. FavoroviD· 1 shared Alison P. KleiniD· 1 shared Carlo ColantuoniiD· 1 shared Daria A. GaykalovaiD· 1 shared David M. McKeaniD· 1 shared Donghui LiiD· 1 shared Elana Judith FertigiD· 1 shared Emily L. FlamiD· 1 shared

Activity by Year

2017-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioinformatics

Alexander V. FavorovORCID

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2 papers

Recent·Most cited

Bayesian copy number detection and association in large-scale studies

Stephen Cristiano, David M. McKean, Jacob Carey, Paige M. Bracci, Paul Brennan, Michael Chou, Mengmeng Du, Steve Gallinger, Michael Goggins, Manal M. Hassan, Rayjean J. Hung, Robert C. Kurtz, Donghui Li, Lingeng Lu, Rachel Ε. Neale, , Robert B. Scharpf

This paper develops a Bayesian method to detect copy number variants and assess their association with disease in large-scale studies, finding deletions near MYC and TUSC3 linked to pancreatic cancer.

BMC Cancer · Sep 7, 2020Peer-reviewedGenetics

PatternMarkers & GWCoGAPS for novel data-driven biomarkers via whole transcriptome NMF

Genevieve Stein-O’Brien, Jacob Carey, Wai Shing Lee, Michael Considine, Alexander V. Favorov, Emily L. Flam, Theresa W. Guo, Sijia Li, Luigi Marchionni, Thomas D. Sherman, Shawn Sivy, Daria A. Gaykalova, Ronald D.G. McKay, Michael F. Ochs, Carlo Colantuoni, Elana Judith Fertig

The paper introduces PatternMarkers and GWCoGAPS to identify data-driven biomarkers from whole-genome data using NMF, demonstrating their application on GTex data.

Bioinformatics · Jan 30, 2017Peer-reviewedBioinformatics