Author

Laura Saiz-Aúz

Fundacion Centro De Investigacion De Enfermedades NeurologicasORCID 0000-0001-9489-5455Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Organism:mouse· 1

Frequent Co-Authors

Agustı́n RuiziD· 1 shared Alberto LleóiD· 1 shared Alberto RábanoiD· 1 shared Alberto Rábano‐Gutierrez· 1 shared Alison GoateiD· 1 shared Amaia M. ArranziD· 1 shared Amanda C. CanoiD· 1 shared Amaya Lavín· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Agustı́n RuizORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintJan 28, 2025

Divergent Effects of APOE3 and APOE4 Human Astrocytes on Key Alzheimer's Disease Hallmarks in Chimeric Mice

Joan Cruz-Sesé, Marta Miron-Alcala, María Alfonso-Triguero…·Amaia M. Arranz

This study shows that APOE3 and APOE4 human astrocytes differentially affect Alzheimer's disease hallmarks in chimeric mice, with APOE3 reducing and APOE4 worsening pathology.

DOI 10.1101/2025.01.28.635271

mousehuman

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Genetic & Genomic MedicinemedRxivPreprintJun 21, 2024

A Novel Susceptibility Locus in NFASC Highlights Oligodendrocytes and Myelination in Progressive Supranuclear Palsy Pathology

Pablo García‐González, Héctor Rodrigo Lara, Yaroslau Compta…·Agustı́n Ruiz

The paper performs a GWAS on PSP in the Iberian population, replicates known risk variants, and identifies a novel locus in NFASC/CNTN2 associated with oligodendrocyte and myelination processes.

3 citations

humanGWAS summary statistics

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