Author
Johns Hopkins UniversityORCID 0000-0001-9493-2084Unclaimed ORCID profile · follow to get notified of new preprints
7 papers
Recent·Most cited
Eric Van Buren, Yi Zhang, Xihao Li…·Russell Bowler
cellSTAAR integrates single-cell ATAC-seq with whole-genome sequencing to enhance power and interpretation of rare variant association tests in non-coding regions.
Xihao Li, Han Chen, Margaret Sunitha Selvaraj…·Amber L. Beitelshees
The paper introduces MultiSTAAR, a statistical framework for multi-trait rare variant analysis in WGS studies, identifying new lipid trait associations in diverse populations.
Yuxuan Wang, Margaret Sunitha Selvaraj, Xihao Li…·Gina Marie Peloso
The paper identifies 83 rare lncRNA variant sets associated with blood lipid levels using WGS data from the TOPMed program and validates some in UK Biobank data.
Zilin Li, Xihao Li, Hufeng Zhou…·Deborah Brown
The paper introduces a framework for detecting noncoding rare variant associations using whole-genome sequencing data, applying it to lipid traits in the TOPMed program.
Margaret Sunitha Selvaraj, Xihao Li, Zilin Li…·Najib Ayas
The paper performs whole genome sequence analysis of plasma lipid levels in 66,329 individuals, identifying new lipid-associated alleles, including rare non-coding variants.
Julie M. Hahn, Yi‐Ping Fu, Michael R. Brown…·Alanna C. Morrison
This study identifies new genetic loci associated with myocardial infarction and coronary heart disease using genome-wide association analyses across multiple cohorts.
Nicola J. Armstrong, Karen A. Mather, Muralidharan Sargurupremraj…·Paul Nyquist
This study identifies genetic loci specific to periventricular and deep white matter hyperintensities, revealing distinct genetic architectures and potential biological mechanisms.