Atrial Proteomic Profiling Reveals a Switch Towards Profibrotic Gene Expression Program in CREM-IbΔC-X Mice with Persistent Atrial Fibrillation
Shuai Zhao, Mohit M. Hulsurkar, Satadru K. Lahiri, Yuriana Aguilar-Sánchez, Elda M. Munivez, Frank U. Müller, Antrix Jain, Anna Malovannaya, Chi Him Kendrick Yiu, Svetlana N. Reilly, Xander H.T. Wehrens
This study identifies proteomic changes in CREM-IbΔC-X transgenic mice with persistent atrial fibrillation, showing a shift from metabolic to profibrotic gene expression programs with age.
Journal of Molecular and Cellular Cardiology · May 1, 2024Peer-reviewedSystems Biology