NeurosciencebioRxivPreprint
Luminal Vascular Dysfunction Drives Rapid Blood Brain Barrier Injury in Hyperglycemic Stroke: Key Roles for Luminal Glycocalyx and Complement
Hansen Chen, Jacqueline A. Frank, Chunfeng Tan…·Gary Kenneth Steinberg
This study identifies vascular luminal glycocalyx loss and complement activation as key drivers of BBB injury in hyperglycemic stroke, showing that targeting complement after reperfusion improves outcomes.