Periklis Paganos

The paper investigates ZGA timing across 61 animal species and finds that genome size to cytoplasm volume ratio predicts ZGA onset.

The paper studies regulatory genome evolution in echinoderms, revealing deep conservation of cis-regulatory elements and chromatin organization, suggesting an ancestral regulatory pattern in animal genomes.

The paper uses single-nucleus transcriptomics to analyze post-metamorphic sea urchin cell types, revealing an all-brain organization and homologues of vertebrate neuronal genes.

The paper uses sea star ovaries to identify conserved ovarian cell types and an endocrine system, suggesting pre-chordate origins of these features in vertebrates.

The paper integrates multi-omics data to refine the gene regulatory network of the sea urchin posterior gut at the single-cell level.

The paper tests the developmental toxicity of plastic pellets on invertebrates from multiple phyla, finding concentration-dependent effects on embryonic development and morphogenesis.

The paper uses scRNA-seq to identify cell types in sea urchin larvae, revealing neuronal and gene regulatory networks with evolutionary implications.

The paper studies skeletal growth in juvenile sea urchins to understand the molecular and cellular mechanisms underlying body plan development and evolution.