Author

Bradley Spencer‐Dene

GlaxoSmithKline (United Kingdom)ORCID 0000-0001-9533-5839Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:rat· 1

Frequent Co-Authors

Dinesh Stanislaus· 1 shared Joel D. Parry· 1 shared Joyce Rendemonti· 1 shared Sara M Bender· 1 shared Sharon Chapman· 1 shared Sreenivas NannapaneniiD· 1 shared Stanley Robinson· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperPharmacology & Toxicology

Dinesh Stanislaus

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1 paper

Recent·Most cited

Pharmacology & ToxicologyNucleic Acid TherapeuticsPeer-reviewedMay 4, 2026

Rat and rabbit whole embryo culture as a new approach method for unlabeled therapeutic antisense oligonucleotide hazard identification with no requirement for microinjection or assisted transfection

Sara M Bender, Sharon Chapman, Sreenivas Nannapaneni…·Dinesh Stanislaus

This paper shows that rat and rabbit whole embryo culture can identify developmental hazards of antisense oligonucleotides without microinjection or transfection, using mipomersen as a test case.

DOI 10.1177/21593337261442471

ratexperimental assay

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