Author

Alex Hughes-Games

University of BristolORCID 0000-0001-9540-040XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Approach:biophysical modeling· 1

Frequent Co-Authors

D. Dunn· 1 shared Fiona M. Diffin· 1 shared Mark D. SzczelkuniD· 1 shared Oscar Enrique Torres MontaguthiD· 1 shared S. McDowall· 1 shared S.J. ShawiD· 1 shared Stephen CrossiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

D. Dunn

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1 paper

Recent·Most cited

Individual Staphylococcus aureus SauUSI restriction endonuclease motors fragment methylated DNA

S.J. Shaw, Alex Hughes-Games, Oscar Enrique Torres Montaguth, S. McDowall, Fiona M. Diffin, D. Dunn, Stephen Cross, Mark D. Szczelkun

This study investigates how the Staphylococcus aureus SauUSI restriction enzyme recognizes and cleaves methylated DNA through ATP-driven translocation and loop formation.

bioRxiv · Oct 16, 2025 · PreprintMicrobiology