Author

David Chen

Howard Hughes Medical InstituteORCID 0000-0001-9552-5659Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

David Chen4 papers · The Lundquist Institute

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:Hi-C· 1 Organism:mouse· 1

Frequent Co-Authors

Adam Yongxin YeiD· 1 shared Camille HebertiD· 1 shared Fred W. Alt· 1 shared Hongli HuiD· 1 shared Job DekkeriD· 1 shared Mariia MikhovaiD· 1 shared Taimor Williams· 1 shared Xin LiniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperImmunology

Adam Yongxin YeORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

ImmunologybioRxivPreprintOct 11, 2026

Robust V(D)J Recombination in the Absence of SA1/2-mediated Chromatin Loops

Zhuo Yang, Yu Fu, Mariia Mikhova…·Fred W. Alt

This study shows that SA1/2 are not essential for V(D)J recombination in G0/G1-arrested cells, but their absence disrupts chromatin loops and long-range Igh recombination, while Ig{kappa} recombination remains functional.

DOI 10.64898/2026.10.10.757971

mouseDNA methylation