Author

Zhuo Yang

Boston Children's HospitalORCID 0000-0003-0285-2891Unclaimed ORCID profile · follow to get notified of new preprints

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Zhuo Yang2 papers · Ludwig-Maximilians-Universität München

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Approach:experimental assay· 2 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:gene regulatory network inference· 1 Assay:Hi-C· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Adam Yongxin YeiD· 2 shared Mariia MikhovaiD· 2 shared Taimor Williams· 2 shared Xin LiniD· 2 shared Camille HebertiD· 1 shared David CheniD· 1 shared David G. SchatziD· 1 shared Fred W. Alt· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersImmunology

Adam Yongxin YeORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintOct 11, 2026

Robust V(D)J Recombination in the Absence of SA1/2-mediated Chromatin Loops

Zhuo Yang, Yu Fu, Mariia Mikhova…·Fred W. Alt

This study shows that SA1/2 are not essential for V(D)J recombination in G0/G1-arrested cells, but their absence disrupts chromatin loops and long-range Igh recombination, while Ig{kappa} recombination remains functional.

DOI 10.64898/2026.10.10.757971

mouseDNA methylation

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ImmunologyProceedings of the National Academy of SciencesPeer-reviewedSep 28, 2026

Human antibody heavy chain variable region exon interacts with 3' regulatory region to form a stable somatic hypermutation center

Ying Guan, Mariia Mikhova, Zhuo Yang…·Xi Chen

The paper demonstrates that a human antibody heavy chain variable region exon forms a stable somatic hypermutation center (SHM-C) through interaction with 3' regulatory regions, supporting AID access and SHM in non-dividing cells.

DOI 10.1073/pnas.2625638123

humanDNA methylation

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