ImmunologybioRxivPreprint
The MRTFs are required for thymocyte trafficking and Treg-mediated immune tolerance
Patrick S. Costello, Diane Maurice, María Benito-Jardón, Richard Treisman
This study shows that MRTF-SRF signaling is critical for thymocyte egress and Treg-mediated immune tolerance, leading to autoimmune phenotypes in MrtfabKOT mice.
DOI 10.64898/2026.10.02.756229